Bundibugyo Virus Vaccine Development and Manufacturing
OFFICE OF ASSISTANT SECRETARY FOR PREPAREDNESS AND RESPONSE
Original Solicitation Links
RRPV-26-13-BundiVx
]bundibugyo virus outbreak response vaccines (bundivx) - rrpv consortium
Contact
Submission Instructions
Description
The Biomedical Advanced Research and Development Authority (BARDA) is seeking proposals through the Rapid Response Partnership Vehicle (RRPV) Consortium to advance investigational Bundibugyo virus (BDBV) vaccine candidates using the VSV vaccine platform. This effort includes manufacturing process development and production of current Good Manufacturing Practice (cGMP) Phase 1 clinical trial material (CTM), with an initial goal of up to 10,000 doses and options for up to 100,000 doses. The project also involves early regulatory engagement to inform critical-path IND-enabling nonclinical studies and a Phase 1 safety and immunogenicity trial. The ultimate goal is to produce cGMP CTM to enable its use in a clinical trial for the ongoing 2026 BDBV outbreak and to identify successful BDBV vaccine candidates for further development. Questions are due June 16, 2026, by 12 p.m. Eastern, and proposals are due by July 2, 2026, at 1 p.m. Eastern. The anticipated period of performance is up to five years from the date of award, with an estimated total U.S. Government funding of approximately $75 million.
Classification Codes
Smart Codes
Specifications
Timeline
Documents
| Title | Date Posted |
|---|---|
| 26-13-BundiVx_QandA_Answers_Clean.docx | Jun 17, 2026 12:00 PM |
| 26-13-BundiVx_QandA_Answers_rev.docx | Jun 18, 2026 12:00 PM |
| RRPV-26-13-BundiVx_RPP_Finalv2.docx | Jun 11, 2026 12:00 PM |
| RRPV-26-13-BundiVx_RPP_Amendment 1.docx | Jun 17, 2026 12:00 PM |
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