Technology Integrator and Accelerator (TIGAR) for Biopreservation

The Advanced Research Projects Agency for Health (ARPA-H) is seeking innovative technologies for stabilizing regenerative tissues and organs, aiming to develop temperature-flexible storage solutions for complex biological systems.

ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)


General
Open
ARPA-H-SOL-26-144
Dec 08, 2026 10:00 PM
Jul 13, 2026 02:28 PM
9 months base + 1 × 9 months option
Request for Information (RFI)
Federal
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Original Solicitation Links
Contact
tigar@arpa-h.gov
Description

The Advanced Research Projects Agency for Health (ARPA-H) is soliciting proposals for the Technology Integrator and Accelerator (TIGAR) Exploratory Topic. This initiative aims to develop enabling technologies for temperature-flexible storage of regenerative tissues and organs, moving beyond current limitations that rely on strictly controlled temperatures. Solutions may incorporate new materials, artificial intelligence/machine learning, high-throughput screening, biological interventions, devices, processing methods, analytical technology, and packaging approaches. Strategies that reduce reliance on strictly controlled temperature zones and can ensure safe storage in a range of environmental conditions are preferred. Innovations at the cellular level without a strategy for deployment in thick tissues will not be considered. The TIGAR program will accept submissions in two intake groups, with solution video due dates on June 8, 2026, and December 8, 2026. Full proposals will follow, with deadlines on August 5, 2026, and February 5, 2027, respectively. The overall funding request for any proposed effort must not exceed $2 million USD over an 18-month period of performance, including two 9-month phases with a down-select decision at the end of Phase 1. Proposers are expected to demonstrate progress towards functional preservation of specific tissue types for 30 days at practical temperatures.

Classification Codes
NAICS541715Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
PSCAN13BIOMEDICAL - ADVANCED DEVELOPMENT
Smart Codes
regenerative tissue storagetemperature-flexible storagebiopreservation technology
Timeline
Apr 24, 2026-Posting Date
May 18, 2026-Webinar Registration Deadline
May 20, 2026-Webinar
Jun 8, 2026-Intake Group 1 - Solution Video Due Date
Aug 5, 2026-Intake Group 1 - Full Proposal Due Date
Dec 8, 2026-Intake Group 2 - Solution Video Due Date
Feb 5, 2027-Intake Group 2 - Full Proposal Due Date
Feb 5, 2027-ISO Closing Date
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