Infectious Disease Medical Interventions Research and Development

The National Institute of Allergy and Infectious Diseases is seeking research and development proposals for infectious-disease vaccine candidates, therapeutic candidates, and in vitro diagnostic platforms under a broad agency announcement.

United States of America > HEALTH AND HUMAN SERVICES, DEPARTMENT OF > NATIONAL INSTITUTES OF HEALTH > NATIONAL INSTITUTES OF HEALTH NIAID


General
Open (active)
HHS-NIH-NIAID-BAA2026-1
Dec 08, 2026 08:00 PM
Oct 09, 2026 08:58 PM
$16,000,000.00
5 years
Request for Proposal (RFP)
Federal
Ask AI about this solicitation
Contact
niaid_dmidomnibusbaaquestions@nih.gov
6701 Rockledge Drive, Bethesda, MD, USA
Submission Instructions
Online
Submit a separate and distinct proposal for each Research Area proposed., Submit the Technical Proposal, Business Proposal, and, when applicable, the PHS Human Subjects and Clinical Trials Information Form as separate documents in eCPS.
Description

The National Institute of Allergy and Infectious Diseases’ Division of Microbiology and Infectious Diseases is soliciting separate proposals for one or more of three research areas: needle-free vaccine candidates progressing through early-phase clinical trials; therapeutic candidates for serious infectious diseases, including viral hemorrhagic fevers, encephalitic paramyxoviruses, picornaviruses, antimicrobial-resistant bacteria, and specified fungal pathogens; and innovative in vitro diagnostic platforms for rapid, broad viral detection and identification. The work may include lead optimization, preclinical and IND-enabling studies, GMP manufacturing, regulatory submissions, clinical trials, diagnostic platform development, clinical validation, and associated technical, business, quality, data-management, and regulatory activities. Proposals must be submitted as separate technical and business proposals, with a technical proposal limit of 75 pages. Multiple cost-reimbursement completion-type contracts are anticipated, with proposed performance periods not exceeding an estimated five years; the solicitation estimates up to $16 million in FY 2027 funding for up to four awards.

Classification Codes
NAICS541715Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
PSCAN12BIOMEDICAL - APPLIED RESEARCH/EXPLORATORY DEVELOPMENT
Smart Codes
infectious disease therapeuticsvaccine developmentin vitro diagnostics
Specifications
Service
Timeline
Nov 6, 2026-Notice of Intent Due
Dec 08, 2026 08:00 PM-Proposals Due
Dec 23, 2026-Inactive Date
Requirements
Scored
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