Mechanisms of Incretin Mimetics and Cancer Risk Research
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This funding announcement aims to support preclinical and patient-based studies investigating the mechanisms through which incretin mimetics, including agonists or antagonists of GLP-1, GIP-1, or dual GLP-1/GIP-1 agents, affect cancer risk. The research should focus on understanding how these agents influence cancer risk, rather than shorter-term outcomes like weight loss and diabetes. Current data suggests these agents may increase the risk of some obesity-related cancers while decreasing the risk of others. Eligible applicants include a wide range of institutions and organizations such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), eligible agencies of the Federal Government, faith-based or community-based organizations, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Indian/Native American Tribal Governments (Other than Federally Recognized), non-domestic (non-U.S.) entities, regional organizations, Tribally Controlled Colleges and Universities (TCCUs), and U.S. territories or possessions. This opportunity falls under the Cancer Cause and Prevention Research assistance listing.
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