NSF X-Labs Initiative: Other Transaction Agreement Solutions Offering
United States of America
Original Solicitation Links
NSF-OTASO-FY26-XLabsInitative
]u.s. national science foundation (nsf) x-labs initiative
Contact
Description
The U.S. National Science Foundation (NSF), Directorate for Technology, Innovation and Partnerships (TIP), is announcing the NSF X-Labs Other Transaction Agreement Solutions Offering (OTASO). This initiative aims to build and accelerate novel platform technologies capable of unlocking new sectors and advancing use-inspired scientific breakthroughs. NSF is soliciting proposals from domestic entities capable of establishing full-time, interdisciplinary R&D teams with the operational autonomy and technical expertise to pursue ambitious missions aligned with NSF X-Labs Topic Announcements. The NSF X-Labs initiative is designed to foster organizations with the structure, resources, and flexibility to tackle large-scale scientific advancements, leading and leveraging novel partnerships across industry, philanthropic, and academic sectors. The program will support dedicated NSF X-Lab teams with substantial operational independence and the flexibility to adapt quickly to an evolving technology landscape. Awards will be milestone-based, with an anticipated Phase 0 lasting approximately 9 to 12 months, followed by a potential Phase 1 of 24 to 36 months, and possible renewal for Phase 2. NSF anticipates awarding no more than $1,500,000 for Phase 0 and up to $50,000,000 per year for Phase 1. Proposals must describe novel platform technologies and clear vision statements for how the work will reshape a field of scientific inquiry or a sector of technology. Key proposal components include Mission, Technology Landscape, Outcomes, Senior/Key Personnel Qualifications, and Team Capabilities Statement. Eligibility is open to any domestic responsible entity, with all lead organizations required to be registered in the System for Award Management (SAM). Research security requirements, including prohibitions on certain U.S. proscribed parties and foreign entities of concern, are strictly enforced.
Classification Codes
Smart Codes
Timeline
Location
Documents
| Title | Date Posted |
|---|---|
| NSF-OTASO-FY26-XLabsInitative - Amended June 23 2026.pdf | Jun 23, 2026 12:00 PM |
| X-Labs FAQ.pdf | Jul 01, 2026 12:00 PM |
| NSF-OTASO-FY26-XLabsInitiative-AttachmentA.pdf | May 14, 2026 12:00 PM |
| NSF-OTASO-FY26-XLabsInitiative.pdf | May 14, 2026 12:00 PM |
| NSF X-Labs OTASO - September 16 Amendment.pdf | Sep 16, 2026 12:00 PM |
| Attachment B - Coming Soon.pdf | Sep 16, 2026 12:00 PM |
| Attachment C - Question Submission Template.pdf | Sep 16, 2026 12:00 PM |
| Attachment B - Conflict of Interest Statement Form.pdf | Sep 18, 2026 12:00 PM |
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