Generative Unconstrained Intelligence Drug Engineering Program
Original Solicitation Links
Description
The Joint Project Lead Chemical, Biological, Radiological, and Nuclear Defense Enabling Biotechnologies (JPL-CBRND-EB) has the mission to accelerate the delivery of medical countermeasures to the warfighter through the development and implementation of platform systems. Generative Unconstrained Intelligence Drug Engineering (GUIDE) is an integrated computational and experimental platform designed to accelerate medical countermeasure development. GUIDE harnesses the power of advanced simulation and machine learning to enable preparedness and facilitate rapid response to protect the warfighter from a diverse and dynamic threat space. GUIDE impacts the discovery and design of biological products (e.g., monoclonal antibodies and vaccines) as well as small molecule drugs by simultaneously optimizing critical quality attributes of safety, efficacy, manufacturability and pharmacokinetics/pharmacodynamics while concurrently accounting for critical design attributes affecting developability and biophysical properties. GUIDE is a collaboration between U.S. interagency, academic and industry partners and is closely linked to the Accelerated Antibodies, Rapid Access to Products in Development (RAPID), Vaccine Acceleration by Modular Progression (VAMP), and Rapid Acquisition and Investigation of Drugs for Repurposing (RAIDR) programs.
Classification Codes
Smart Codes
Timeline
'Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)' Opportunities
The Defense Health Agency is planning an 8(a) set-aside on-ramp for multiple awards under the OMNIBU...
The Centre de services scolaire de la Capitale is seeking qualified professional laboratory firms fo...
Canoe Procurement Group of Canada and Sourcewell are seeking proposals for laboratory and science eq...
The New Mexico Environment Department is seeking multidisciplinary scientific, engineering, environm...
Los Angeles County's Chief Sustainability Office is seeking qualified CAPSMA contractors for as-need...
The Defense Advanced Research Projects Agency's Defense Sciences Office is seeking innovative basic ...
The Department of War is seeking proposals from U.S. universities to purchase research equipment and...
Sourcewell, a Minnesota local government unit and service cooperative, is requesting proposals for l...
Sourcewell is requesting proposals for laboratory and science equipment, supplies, related technolog...
The Saskatchewan Association of Rural Municipalities, through the Canoe Procurement Group of Canada ...
The University of Connecticut is seeking consulting firms to provide research administration, resear...
The Louisiana Office of State Procurement is seeking referral laboratory testing services for Centra...
The Indiana Department of Administration, on behalf of the Indiana State Department of Toxicology an...
The U.S. Navy's Naval Information Warfare Center Pacific is seeking small businesses for IT services...
The National Science Foundation is seeking proposals for research and development in other biologica...
The National Science Foundation is offering grants for planning, developing, creating, enhancing, an...
The Department of Defense is seeking proposals from accredited U.S. institutions of higher education...
The Department of War is seeking proposals from accredited U.S. institutions of higher education for...
The National Science Foundation is seeking proposals for novel technologies through its Small Busine...
The Department of Defense is seeking proposals from institutions of higher education in eligible sta...
The Indiana Department of Administration, on behalf of the Indiana Veterans' Home, is seeking clinic...
The New York State Department of Environmental Conservation is seeking vendor information on commerc...
The National Science Foundation is seeking proposals for research and development in other environme...
The U.S. Department of the Navy is seeking professional engineering and technical support services f...
The Town of Queen Creek, Arizona, is seeking a qualified civil construction quality assurance firm t...