Advancing Drug Repositioning and Combination Therapy for Alzheimer's Disease Research

The Department of Health and Human Services is seeking applications for research grants focused on advancing drug repositioning and combination therapy development for Alzheimer's disease and related dementias using mouse models.

General
Open (posted)
PAR-25-374
May 07, 2028 12:00 PM
Dec 30, 2024 12:00 PM
$1,000,000.00
Grant
Federal
Ask AI about this solicitation
Contact
NIH Grants Information
grantsinfo@nih.gov
Description

This funding opportunity invites applications proposing the use of mouse models for rigorous preclinical testing of drugs and drug combinations for the treatment and prevention of Alzheimer's disease and related dementias (AD/ADRD). The initiative supports the testing of repurposable or investigational drug candidates, including combinations with non-pharmacologic interventions, to establish proof of concept for rational drug repurposing and combination therapy development. Eligible applicants include a wide range of institutions such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions, eligible agencies of the Federal Government, faith-based or community-based organizations, Hispanic-serving Institutions, Historically Black Colleges and Universities, Indian/Native American Tribal Governments, non-U.S. entities, regional organizations, Tribally Controlled Colleges and Universities, and U.S. territories or possessions. The funding is categorized under discretionary health grants, with an estimated total program funding of $1,000,000 and an award ceiling of $1,000,000. The Assistance Listing number is 93.866 for Aging Research.

Classification Codes
NAICS541714Research and Development in Biotechnology (except Nanobiotechnology)
PSCAN12BIOMEDICAL - APPLIED RESEARCH/EXPLORATORY DEVELOPMENT
Smart Codes
mouse modelsdrug developmentclinical trial researchhealth research grantsdrug repositioningcombination therapyalzheimers disease researchdementia researchbioinformaticspreclinical testing
Timeline
Dec 30, 2024-Post Date
May 7, 2028-Close Date
'Research and Development in Biotechnology (except Nanobiotechnology)' Opportunities
OMNIBUS IV Military Medical Research and Development On-Ramp

The Defense Health Agency is planning an 8(a) set-aside on-ramp for multiple awards under the OMNIBU...

Due in 12 months•United States of America > DEPT OF DEFENSE > DEFENSE HEALTH AGENCY (DHA) > DEFENSE HEALTH AGENCY
Animal Biotechnology SBIR

The National Science Foundation is seeking proposals for animal biotechnology research and developme...

Due in 9 months•United States of America > NATIONAL SCIENCE FOUNDATION
Cell and Tissue Engineering

The National Science Foundation is seeking proposals for cell and tissue engineering research and de...

Due in 9 months•United States of America > NATIONAL SCIENCE FOUNDATION
Plant Biotechnology Research and Development

The National Science Foundation is seeking proposals for plant biotechnology research and developmen...

Due in 9 months•United States of America > NATIONAL SCIENCE FOUNDATION
Sequence-to-Function Bioengineering Research Teams

The National Science Foundation is seeking written proposals from bioengineering teams to develop tr...

Due in 4 months•United States of America > NATIONAL SCIENCE FOUNDATION > TIP - CORE PROGRAMS
Professional Laboratory Services Qualification

The Centre de services scolaire de la Capitale is seeking qualified professional laboratory firms fo...

Due in about 24 hours•Centre de services scolaire de la Capitale > Services des ressources materielles
Biomedical Technologies SBIR

The National Science Foundation is seeking proposals for biomedical technologies under the SBIR prog...

Due in 9 months•United States of America > NATIONAL SCIENCE FOUNDATION
Synthetic Biology and Metabolic Engineering Research

The National Science Foundation is seeking proposals for research and development in synthetic biolo...

Due in 9 months•United States of America > NATIONAL SCIENCE FOUNDATION
Life Science Research Tools

The National Science Foundation is seeking proposals for the development of life science research to...

Due in 9 months•United States of America > NATIONAL SCIENCE FOUNDATION
Other Biological Technologies

The National Science Foundation is seeking proposals for research and development in other biologica...

Due in 9 months•United States of America > NATIONAL SCIENCE FOUNDATION
Joint Warfighter Medical Research and Development Award

The Department of War is seeking research and development proposals for medical advancements through...

Due in 29 days•United States of America > DEPT OF DEFENSE
NIH Biorepository Biobanking and Informatics Services

The National Institutes of Health is seeking capability statements from small businesses able to pro...

Due in 2 days•United States of America > HEALTH AND HUMAN SERVICES, DEPARTMENT OF > NATIONAL INSTITUTES OF HEALTH > NATIONAL INSTITUTES OF HEALTH NIDA
Referral Laboratory Testing Services

The Louisiana Office of State Procurement is seeking referral laboratory testing services for Centra...

Due in 18 days•Louisiana > Office of State Procurement
Statewide Toxicology Services

The Indiana Department of Administration, on behalf of the Indiana State Department of Toxicology an...

Due in about 1 month•Indiana > Department of Administration > Procurement Division > Indiana State Department of Toxicology > Indiana Department of Health
Defense Sciences Office Revolutionary Research BAA

The Defense Advanced Research Projects Agency's Defense Sciences Office is seeking innovative basic ...

Due in 10 months•United States of America > DEPT OF DEFENSE > DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
Indiana Veterans' Home Clinical Laboratory Services

The Indiana Department of Administration, on behalf of the Indiana Veterans' Home, is seeking clinic...

Due in 10 days•Indiana > Indiana Veterans' Home
Laboratory and Science Equipment, Supplies, and Related Services

Canoe Procurement Group of Canada and Sourcewell are seeking proposals for laboratory and science eq...

Due in 22 days•Rural Municipalities of Alberta
Nutrition Obesity Research Centers Grant

The National Institute of Diabetes and Digestive and Kidney Diseases is offering grants to establish...

Due in 1 day•United States of America > Department of Health and Human Services > National Institutes of Health > National Institute of Diabetes and Digestive and Kidney Diseases
Emerging Health Innovators Biomedical Research Initiative

The Advanced Research Projects Agency for Health is seeking early-career investigators and their org...

Due in 4 months•United States of America > HEALTH AND HUMAN SERVICES, DEPARTMENT OF > NATIONAL INSTITUTES OF HEALTH > ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
Microbiome and Microbial Diversity Research

The National Science Foundation is seeking proposals for research and development in microbiome and ...

Due in 9 months•United States of America > NATIONAL SCIENCE FOUNDATION
Drug Discovery Research and Development

The National Science Foundation is seeking proposals for drug discovery research and development thr...

Due in 9 months•United States of America > NATIONAL SCIENCE FOUNDATION
Handheld Burn Sepsis Risk Assessment Device Development

The Defense Health Agency intends to award a sole-source contract for development of a handheld devi...

Due in 15 days•United States of America > DEPT OF DEFENSE > DEFENSE HEALTH AGENCY (DHA) > DEFENSE HEALTH AGENCY
Laboratory and Science Equipment, Supplies, Technology, and Services

Sourcewell, a Minnesota local government unit and service cooperative, is requesting proposals for l...

Due in 23 days•Minnesota > Sourcewell
Laboratory and Science Equipment and Services

Sourcewell is requesting proposals for laboratory and science equipment, supplies, related technolog...

Due in 23 days•Sourcewell
Laboratory and Science Equipment, Supplies, Technology, and Services

The Saskatchewan Association of Rural Municipalities, through the Canoe Procurement Group of Canada ...

Due in 23 days•Saskatchewan > Saskatchewan Association of Rural Municipalities
Comments
Correspondences
Custom Fields