Research Grants for Mind-Body Interventions and Emotional Well-being

The National Center for Complementary and Integrative Health (NCCIH) is seeking applications for research grants focused on how mind and body interventions impact emotional well-being and whole person health, utilizing a two-phased R61/R33 funding mechanism.

General
Open (posted)
PAR-25-449
Jun 07, 2028 12:00 PM
Sep 26, 2025 12:00 PM
Grant
Federal
Ask AI about this solicitation
Contact
NIH Grants Information
grantsinfo@nih.gov
Description

The National Center for Complementary and Integrative Health (NCCIH) is soliciting applications for research grants to investigate the impact of mind and body interventions on mechanisms of emotional well-being (EWB) and their association with whole person health (WPH). This initiative supports rigorous, well-powered mechanistic research studies with strong preliminary data, examining the effects of interventions such as mindfulness meditation, yoga, acupuncture, and massage on EWB as a primary outcome and the Whole Person Health Index as a secondary outcome. The funding will be awarded through a two-phased R61/R33 mechanism. The initial R61 phase will focus on establishing feasibility benchmarks for proposed mechanistic clinical trials, with the subsequent R33 phase contingent upon successful completion of the R61 milestones for full-scale trials. Applications must provide preliminary data comparable in quality and quantity to an R01 proposal. Eligibility is restricted to specific U.S.-based institutions and organizations, excluding foreign entities and components.

Classification Codes
NAICS541720Research and Development in the Social Sciences and Humanities
PSCAN52MENTAL HEALTH - APPLIED RESEARCH/EXPLORATORY DEVELOPMENT
Smart Codes
mind body interventionsemotional well-being researchwhole person healthclinical trial fundingr61 r33 mechanismintegrative health researchpsychological input researchphysical input researchhealth outcomes researchnih grant funding
Timeline
Sep 26, 2025-Post Date
Jun 7, 2028-Close Date
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